認明正貨
Identify Authentic BOTOX®
療程前先查證每半年由廠商 Allergan Aesthetics 授予醫療中心的 BOTOX®保妥適®原廠供應證書。確保讓擁有認可資格的專業醫生為你進行療程，獲得最全面的保障！ Before taking BOTOX® treatment, please check the certificate issued every 6 months from Allergan Aesthetics. Consult qualified doctors and beauty centres to ensure receiving reliable treatment.
‡: Medical Insight, Inc 2018. Global Facial Injectables Market Study. December 2018. Based on worldwide neurotoxins market 2017 (in sales value).
*: Allergan. Unpublished Data. INT/0292/2018(1). March 2019. #: BOTOX® Prescribing Information. HK-41906. May 2013.
†: Allergan. Data on File. REF-74184.UNPUBLISHED DATA: BOTOX® number of vials shipped as of March 2019 INT/0292/2018(1). March 2019.
References: 1. Trindade de Almeida A et al. Dermatol Surg 2015; 41: S19-S28. 2. Yu W et al. J Cosmet Laser Ther. 2018Oct;20(5):278-286. 3. U.S. Food and Drug Administration, Department of Health & Human Services. Botox approval letter 85-0226 & 85-0227, December 29, 1989. 4. Allergan. Unpublished Data. INT-BCT-2050129 – Worldwide BOTOX® marketing authorization status. October 2020. 5. Allergan. Unpublished Data. INT-BCT-2050035. BOTOX® vs competitors – number of peer reviewed articles vs competitors. February 2020. 6. Flaharty, P. (2014, April 8). Your facial wrinkles are dynamic or static. Retrieved February 10, 2022, from https://www.news-press.com/story/life/wellness/2014/04/08/beauty-tips-your-facial-wrinkles-are-dynamic-or-static/7432785/. 7. DasGupta BR. Structures of botulinum neurotoxin, its functional domains, and perspectives on the crystalline type A toxin. In: Jankovic J, Hallet, M., ed. Therapy with Botulinum Toxin. New York, NY: Marcel Decker, Inc; 1994: 15-39. 8. Coffield JA, Considine RV, Simpson LL. The site and mechanism of action of botulinum neurotoxin. In: Jankovic J, Hallet, M., ed. Therapy with Botulinum Toxin. New York, NY: Marcel Dekker, Inc; 1994:3-13. 9. Schantz EJ, Johnson EA. Preparation and characterization of botulinum toxin type A for human treatment. In: Jankovic J, Hallet, M., ed. Therapy with Botulinum Toxin. New York, NY: Marcel Dekker, Inc; 1994:41-49. 10. Simpson LL. The actions of clostridial toxins on storage and release of neurotransmitters. In: Harvey AL, ed. Natural and Synthetic Neurotoxins (Neuroscience Perspectives). San Diego, CA: Academic Press; 1993:278-317. 11. Black JD, Dolly JO. Interaction of 125I-labeled botulinum neurotoxins with nerve terminals II. Autoradiographic evidence for its uptake into motor nerves by acceptor-mediated endocytosis. J Cell Biol. 1986;103(2):535-544. 12. Lebeda FJ, Hack DC, Bentry MK. Theoretical analyses of the functional regions of the heavy chain of botulinum neurotoxin. In: Jankovic J, Hallet M, ed. Therapy with Botulinum Toxin. New York, NY: Marcel Dekker, Inc; 1994:51-61. 13. Harvey AL. Presynaptic toxins. In: Smythies JR, Bradley RJ, ed. International Review of. 14. Neurobiology. San Diego, CA: Academic Press; 1990:201-239. 15. Tremaine AM, McCullough JL. Clin Cosmet Investig Dermatol. 2010;3:15–23. 16. Stotland MA et al. Plast Reconstr Surg 2007; 120(5):1386-9. 17. Beer KR et al. J Drugs Dermatol 2011;10:39-41. 18. De Boulle K et al. Dermatol Surg. 2018;44[11]:1437-1448. 19. Hyperhidrosis- Causes and Treatment of Enhanced Sweating. Dtsch Arztebl Int. 2009 Jan; 106(3):32-37. 20. Aesthetic Surg J. 2012 Feb;32(2):238-244. 21. J Am Acad Dermatol. 2007 Apr; 56(4):604-11. 22. He J, Wang T and Dong J. Journal of Dermatological Treatment. 2012 23: 461–464. 23. Naumann M and Lowe NJ. BMJ 2001;323:1–4. 24. Lowe NJ et al. J Am Acad Dermatol. 2007;56(4):604-611. 25. U.S. Food and Drug Administration, Department of Health & Human Services. Botox approval letter SUPPL-5303, October 2, 2017.
BOTOX®保妥適®(Botulinum Toxin Type A)藥品註冊編號: HK-41906. BOTOX®為醫生處方藥物，請向醫生或醫學美容中心
諮詢切合您獨特需要的專屬療程方案。療程效果因人而異。療程後如有任何不良反應，請即向醫生查詢
© 2023 Allergan Aesthetics. All rights reserved. All adverse events should be reported to drugsafety.pv@abbvie.com. HK-BCT-230023.
Approval date: 23/Mar/23
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